285 The use of dipeptidyl peptidase-4 inhibitors (DPP-4) in CF-related diabetes (CFRD)
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چکیده
منابع مشابه
Dipeptidyl Peptidase-4 (DPP-4) Inhibitors In the Management of Diabetes.
PHARMACOLOGY Research into the role of gut hormones in the regulation of pancreatic beta-cell function has led to new targets in the management of type-2 diabetes. It is known that eating food leads to the release of multiple hormones that regulate gut motility, the secretion of gastric and pancreatic enzymes, the contraction of the gallbladder, and the absorption of various nutrients.3 Several...
متن کاملDipeptidyl peptidase-4 (DPP-4) inhibitors for type 2 diabetes mellitus.
BACKGROUND In type 2 diabetes mellitus there is a progressive loss of beta-cell function. One new approach yielding promising results is the use of the orally active dipeptidyl peptidase-4 (DPP-4) inhibitors like sitagliptin and vildagliptin. OBJECTIVES To assess the effects of dipeptidyl peptidase-4 (DPP-4) inhibitors for type 2 diabetes mellitus. SEARCH STRATEGY Studies were obtained from...
متن کاملThe Dipeptidyl Peptidase (DPP)-4 Inhibitors for Type 2 Diabetes Mellitus in Challenging Patient Groups
Treating hyperglycemia is a critical aspect of managing type 2 diabetes mellitus (T2DM), but can be especially challenging in patients from vulnerable groups such as those with chronic kidney disease, African Americans, and older people. The dipeptidyl peptidase (DPP)-4 inhibitors are relatively new oral antidiabetes drugs that have been incorporated into treatment algorithms over the past few ...
متن کاملDipeptidyl-peptidase-4 inhibitors for treatment of type 2 diabetes.
OBJECTIVE To assess the efficacy and safety of dipeptidyl peptidase-4 (DPP-4) inhibitors compared with metformin as monotherapy, or with other commonly used hypoglycaemic drugs combined with metformin, in adults with type 2 diabetes mellitus. DESIGN Systematic review and meta-analysis of randomised controlled trials. DATA SOURCES Medline, Embase, the Cochrane Library, conference proceedings...
متن کاملEfficacy of different dipeptidyl peptidase-4 (DPP-4) inhibitors on metabolic parameters in patients with type 2 diabetes undergoing dialysis
Hyperglycemia is associated with increased mortality and morbidity in patients with type 2 diabetes mellitus (T2DM) who are undergoing dialysis. Although dipeptidyl peptidase-4 (DPP-4) inhibitors have been widely used in end-stage renal disease (ESRD) patients with T2DM, there are few studies on their efficacy in this population. We studied the effect of 3 different DPP-4 inhibitors on metaboli...
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ژورنال
عنوان ژورنال: Journal of Cystic Fibrosis
سال: 2017
ISSN: 1569-1993
DOI: 10.1016/s1569-1993(17)30624-0